Ultrasonic Homogenizer

Ultrasonic Homogenizer

  • FAPAN
  • Homogenization

    1. NanoScale Certification

    2. 2017/11/21
    3. 2020/11/21

    1. Certificate of Nanotechnology

    2. 2017/11/21
    3. 2020/11/21
Introduction Application Specification Advantage Of Using Nanotechnology Manual And Maintenance Safety And Package

Ultrasonic Homogenizer is one of the methods which widely used to homogenize solutions. This device operates based on the conversion of an electric current into a mechanical vibration and generation of intense sonic pressure waves in liquid media. Under the right conditions, the pressure waves in liquid create flows and cause rapid formation of microbubbles. Growth and agglomeration of these bubbles until reaching their maximum size, and eventually their implosion produce enormous amount of heat. This phenomenon is called cavitation. The bubbles implosion generates a shock wave with enough energy to break covalent bonds. Homogenization is executed using turbulent flows and shear forces which resulted from sound vibrations and bubbles implosion, respectively.

An ultrasonic homogenizer is made up of three major parts, i.e. generator, transducer and booster. The ultrasonic generator converts the input single-phase electricity of 220 VAC, 50-60 Hz into high-frequencies required for the ultrasonic system (15 to 40 kHz). The ultrasonic transducer transforms the electrical oscillations to the mechanical energy through a piezoelectric and then transmits them to the booster. The booster amplifies the vibration amplitude and transfers it to the probe. It should be noted that the probe size is directly proportional to the output power.

Some applications of this instrument are as follows:

  • Synthesis of different nanostructures including graphene and carbon nanotubes
  • Surface coatings with nanoparticles
  • Dispersion of nanoparticles
  • Sonochemistry and sonoelectrochemistry
  • Cracking, petroleum sulfur removal, catalysts efficiency improving
  • Sewage purification and refining
  • Extraction of herb extract and other effective materials
  • Disruption of bacteria, plant cells, soft and hard cell tissue, nucleic material and yeasts
  • Cell extract preparation
  • Preparation and isolation of enzymes
  • DNA extraction or preparation of fragmented liposomes
  • Production of antigen and many other applications.

The Ultrasonic Homogenizing systems provided by this company are designed and produced in nine different models. Details of technical specifications are presented in the following Table.

 

Many of the synthesis processes of nanoparticle and nanostructured materials rely on homogenization and in some of the early stages of their processes need to be prepared as emulsions and suspensions. Thus, the application of ultrasonic homogenizer in production of nanoparticles, nanostructured materials and generally, in nanotechnology is very broad and fundamental.

  • To increase the apparatus service lifetime, try to use it in operation periods of 3-minutes, 50% power and even working pulse time of 50%.
  • Adjust the maximum time on device timer to 24 minutes to protect apparatus and extend tool life. It does not bring any constraint because the device can be used again after a few minutes.
  • Despite installing a fan inside the probe chamber to cool down the transducer, it is better to allow the ultrasonic generator to be cool in regular intervals. The temperature variations can change the piezoelectric working point and prevent your condition from reproducibility.
  • In case of frequent use, the device sound may change or during operation, the bubbles form with delay; in such case, change the device output power to zero and allow transducer to cool down.
  • Occurrence of noisy-like sound or splashing, which results from intense vibrations, at the beginning of the ultrasonic treatment is the sign of transducer failure. In this case, send the device to the company to be fixed.
  • Occasionally, touch the probe tip with your nail; if it was rough enough to be sensed, replace it or send the probe to the company for possible repair. The damaged probe should be replaced; otherwise, it may impair the generator or the ultrasonic transducer.
  • After each session, clean the titanium probe with water and alcohol or acetone. If the stains still remain, gently polish the probe surface with sandpaper 1000 or so, until it becomes shiny.
  • For more details on how to use the device, refer to the device catalog and user guide.
  • Use the thermocouple thermometer since the ultrasonic waves damage thermometers like Pt 100 and erase the numbers on the glass thermometer.
  • Be careful the container is free from cracks because ultrasonic waves can easily break the container and spoil the solution.
  • Allow the ultrasonic generator to be cool in regular intervals. The temperature variations can change the piezoelectric working point and prevent your condition from reproducibility.
  • As far as possible use the device in its own vessel because ultrasonic waves may cause hearing loss in the long run; furthermore, do not stare at the ultrasonic vessel.
  • The probe is sensitive to impact, so be careful during replacing or transporting the probe.
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